Basement membrane collagen of renal glomerulus.

Basement membrane collagen.

Collagen Fibrils within the Renal Glomerulus

The fine structure of the frog glomerulus has been described in detail by Pak Poy (2); the present observations confirm his findings as far as its principal structure is concerned. He pointed out that the main morphological difference between the frog glomerulus and those of mammals is in the basement membrane, that is, the structure between endothelial and epithelial (podo-cyte) cells. Beneath...

Study of Basement Membrane Type IV Collagen Appearance in the Brain Choroids Plexus of Mouse Fetuses

Introduction & Objective: The brain choroids plexus (BCP) plays an important role in the cerebrospinal fluid (CSF) production, but its characterization is still incomplete. Collagen type IV, is one of the most important proteins of basement membrane (BM) and extracellular matrix (ECM) of BCP. In the present study we investigated the differential period of type IV collagen in basement membrane...

Thin basement membrane nephropathy and renal transplantation.

The clinical implications of thin basement membrane nephropathy (TBMN) in renal transplantation must be considered from the perspectives of both the allograft recipient and the donor. Most individuals with TBMN have a benign course, but some develop end-stage renal failure (ESRF) and undergo transplantation. ESRF in patients with TBMN often results from the presence of additional glomerular or ...

Glomerular basement membrane thickening in renal allografts.

Diffuse thickening of glomerular basement membranes (GBM) was optically observed in the renal grafts of 15 patients (21 specimens) among 70 recipients (128 specimens). Most of these specimens with diffuse GBM thickening were examined ultrastructurally. All cases with the above change were only found in allografts. The correlation was observed between the degree of GBM thickening and the clinica...